. Author manuscript; available in PMC: 2015 Sep 8.

Published in final edited form as: Am J Orthod Dentofacial Orthop. 2013 Apr;143(4):499–506. doi: 10.1016/j.ajodo.2012.10.023

Table.

Comparison of the rabbits 3 weeks after injection of either BoNT/A or saline solution into a masseter muscle (mean ± standard deviation, n)

	BoNT/A	Saline solution	P value
Body weight (kg)	4.04 ± 0.27, 21	3.95 ± 0.36, 19	0.40
Mastication
Rate (Hz)	3.3 ± 0.33, 21	3.41 ± 0.29, 19	0.52
Side (% on injected side)	58 ± 24, 21	49 ± 29, 19	0.52
Efficiency (cycles/1-g bolus)	126 ± 39, 5	117 ± 20, 6	0.65
Bite force from tetanized masseter (kg)
Noninjected side	0.98 ± 0.68, 18	1.04 ± 0.43, 18	0.40
Injected side	0.22 ± 0.21, 16	1.38 ± 0.90, 16	0.00^*
P value between sides	0.00^*	0.16
Incisor eruption rate (mm/day)
Maxillary noninjected side	0.24 ± 0.09, 16	0.34 ± 0.11, 16	0.01^*
Maxillary injected side	0.24 ± 0.09, 16	0.32 ± 0.09, 16	0.02^*
Paired P value between sides	0.81	0.45
Mandibular noninjected side	0.38 ± 0.14, 16	0.49 ± 0.12, 16	0.02^*
Mandibular injected side	0.32 ± 0.14, 16	0.46 ± 0.16, 16	0.01^*
Paired P value between sides	0.06	0.45

Statistically significant difference.