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. Author manuscript; available in PMC: 2015 Sep 8.
Published in final edited form as: Am J Orthod Dentofacial Orthop. 2013 Apr;143(4):499–506. doi: 10.1016/j.ajodo.2012.10.023

Table.

Comparison of the rabbits 3 weeks after injection of either BoNT/A or saline solution into a masseter muscle (mean ± standard deviation, n)

BoNT/A Saline solution P value
Body weight (kg) 4.04 ± 0.27, 21 3.95 ± 0.36, 19 0.40
Mastication
  Rate (Hz) 3.3 ± 0.33, 21 3.41 ± 0.29, 19 0.52
  Side (% on injected side) 58 ± 24, 21 49 ± 29, 19   0.52
  Efficiency (cycles/1-g bolus) 126 ± 39, 5 117 ± 20, 6 0.65
Bite force from tetanized masseter (kg)
  Noninjected side 0.98 ± 0.68, 18 1.04 ± 0.43, 18 0.40
  Injected side 0.22 ± 0.21, 16 1.38 ± 0.90, 16 0.00*
  P value between sides 0.00* 0.16
Incisor eruption rate (mm/day)
  Maxillary noninjected side 0.24 ± 0.09, 16 0.34 ± 0.11, 16 0.01*
  Maxillary injected side 0.24 ± 0.09, 16 0.32 ± 0.09, 16 0.02*
  Paired P value between sides 0.81 0.45
  Mandibular noninjected side 0.38 ± 0.14, 16 0.49 ± 0.12, 16 0.02*
  Mandibular injected side 0.32 ± 0.14, 16 0.46 ± 0.16, 16 0.01*
  Paired P value between sides 0.06 0.45
*

Statistically significant difference.