Table 1.
Characteristics of the patients with COPD
| Variables | Without OP (n=11) | OP (n=19) | P-value |
|---|---|---|---|
| Age | 71.7±9.1 | 70.2±9.0 | 0.9370 |
| Sex (n) | |||
| Male | 10 | 18 | 0.6855 |
| Female | 1 | 1 | |
| Smoke status (n) | |||
| Never smoke | 0 | 1 | 0.4603 |
| Smoking | 0 | 0 | |
| Ex-smoking | 11 | 18 | |
| BMI, kg/m2 | 27.7±4.2 | 23.5±3.9 | 0.0104 |
| FFMI, kg/m2 | 19.3±2.3 | 17.4±2.1 | 0.0328 |
| CAT | 5.0±3.8 | 8.1±5.8 | 0.0424 |
| Pulmonary function test | |||
| FEV1a, % | 42.6±15.8 | 44.3±14.2 | 0.758 |
| FVC, % | 67.0±14.5 | 64.1±14.0 | 0.5944 |
| FEV1/FVC, % | 50.6±10.5 | 49.2±12.1 | 0.7540 |
| Bone mineral density | |||
| Lumbar spine, g/cm2 | 1.05±0.05 | 0.86±0.04 | 0.0481 |
| Total hip, g/cm2 | 0.95±0.04 | 0.73±0.03 | <0.0001 |
| Femoral neck, g/cm2 | 0.82±0.04 | 0.62±0.02 | <0.0001 |
Notes: Values are expressed as the mean ± SD unless otherwise indicated;
a
the prevalence on without OP group was 10% in stage GOLD I and II, 20% in stage GOLD III, and 6.7% in stage GOLD IV; prevalence of OP group was 23.3% in stage GOLD I and II, 30% in stage GOLD III, and 10% in stage GOLD IV; control vs COPD.
Abbreviations: BMI, body mass index; FFMI, fat-free mass index; CAT, COPD assessment test; FEV1, forced expiratory volume in the 1 second; FVC, forced vital capacity; OP, osteoporosis; SD, standard deviation.