Table 2.
In vitro biocompatibility studies of layered double hydroxides (LDHs) toward various cell lines
| Sample | Type of LDH | Biocompatibility with cell type | Reference |
|---|---|---|---|
| 1 | Etoposide (VP16)–Mg/Al LDHs | Human GES-1 cells | Qin et al128 |
| 2 | Perindopril erbumine LDHs | Human liver cell line | Hussein et al24 |
| 3 | pEF-eGFP LDHs | HEK 293T cells | Xu et al174 |
| 4 | Protein gene LDHs | Monkey kidney (Vero3) cells | Masarudin et al183 |
| 5 | Salicylic acid ZnLHs | Monkey kidney (Vero3) cells | Ramli et al184 |
| 6 | LDH-AgNPbio | Permanent lung fibroblast cell line (V79) | Marcato et al146 |
| 7 | Para-aminosalicylic acid–Zn/Al LDHs | Fibroblast 3T3 cells and human normal lung cells (MRC-5) | Saifullah et al23 |
| 8 | Para-aminosalicylic acid ZnLH | Fibroblast 3T3 cells and human normal lung cells (MRC-5) | Saifullah et al153 |
| 9 | Isoniazid–Mg/Al LDHs | Fibroblast 3T3 cells and human normal lung cells (MRC-5) | Saifullah et al154 |
| 10 | Isoniazid–Zn/Al LDHs | Fibroblast 3T3 cells and human normal lung cells (MRC-5) | Saifullah et al155 |
| 11 | Cinnamic acid ZnLH | Fibroblast cells (3T3) | Mohsin et al42 |
| 12 | Cinnamic acid into Zn/Al LDHs | HDF cells | Mohsin et al101 |
| 13 | Benzophenone-4–Zn/Al LDHs | HDF cells | Mohsin et al101 |
| Eusolex® 232–Zn/Al LDHs | HDF cells | Mohsin et al101 | |
| 14 | Benzophenone-9–Zn/Al LDHs | HDF cells | Mohsin et al101 |
| 15 | Ellagic acid ZnLH | Normal human breast epithelial MCF-10A cells and murine fibroblast 3T3 cells | Hussein-Al-Ali et al185 |
| 16 | Levodopa and Zn/Al LDHs | PC 12 cell model | Kura et al178 |
Abbreviations: NP, nanoparticle; ZnLHs, zinc layered hydroxides.