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. 2015 Sep 2;10:5609–5633. doi: 10.2147/IJN.S72330

Table 3.

In vivo biocompatibility of layered double hydroxides (LDHs) using animal models

Sample Type of LDH Animal model Reference
1 Indomethacin–Mg/Al LDHs Both sexes
Swiss mice
Del Arco et al187
2 Ketoprofen–Mg/Al LDHs Mice Silion et al192
3 Ketoprofen–Zn/Al LDHs Mice Silion et al192
4 Acetylsalicylic acid–dextran LDHs Rabbits Dong et al160
5 LDH nanoparticles Mice Yu et al193
6 Mg/Al LDH nanoparticles Mice Flesken-Nikitin et al194
7 Levodopa–Zn/Al LDHs Rats Kura et al195