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. 2015 Sep 1;8:2383–2390. doi: 10.2147/OTT.S49688

Figure 3.

Figure 3

Algorithm for CNL diagnosis and treatment.

Notes: The presence of a membrane proximal CSF3R mutation in a patient with predominantly neutrophilic granulocytosis should be sufficient for the diagnosis of CNL.

Abbreviations: CNL, chronic neutrophilic leukemia; PB, peripheral blood; JAK2, Janus kinase 2; AML, acute myeloid leukemia.