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. 2015 Sep 1;10:5529–5542. doi: 10.2147/IJN.S83929

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© 2015 Mattos et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Inhibitory effects of nanoemulsions on Leishmania amazonensis in vitro tested 24 hours after the preparation of formulations.

Notes: Adherent THP-1 cells were infected at a ratio of 1:10 cell/parasite L. amazonensis and treated for 48 hours with free SC and SC loaded into nanoemulsions in a concentration range of 0.375–20 µg·mL⁻¹. Results are expressed as the mean ± SD of the percent inhibition of parasite growth (n=3).

Abbreviations: LP20, soybean lecithin and polysorbate 20; LP80, soybean lecithin and polysorbate 80; SC, (E)-3-(3-nitrophenyl)-1-(3,4,5-trimethoxyphenyl) prop-2-en-1-one; SD, standard deviation; SP20, sorbitan monooleate and polysorbate 20; SP80, sorbitan monooleate and polysorbate 80.