Table 1.
Comparison of descriptive characteristics and peak CPET variables in 107 patients with COPD in the retrospective study
| Group Variables | PPR-OT group
|
Control group
|
Comparison P-values |
|---|---|---|---|
| n=46 (M:F, 44:2)
|
n=61 (M:F, 57:4)
|
||
| Mean ± SD | Mean ± SD | ||
| Descriptive characteristics | |||
| Age (years) | 68.7±7.1 | 68.5±6.7 | 0.4185 |
| BMI (kg/m2) | 19.7±2.7 | 19.0±3.1 | 0.3866 |
| FEV1(L) | 0.80±0.23 | 0.81±0.24 | 0.5381 |
| FEV1/FVC (%) | 36.7±8.4 | 37.1±13.6 | 0.5689 |
| FEV1(% predicted) | 30.6±9.1 | 30.4±9.7 | 0.4635 |
| FVC (L) | 2.25±0.66 | 2.28±0.72 | 0.5905 |
| FVC (% predicted) | 70.3±18.6 | 71.4±21.4 | 0.6199 |
| Heart rate (beats/min) | 88.9±13.9 | 89.8±12.6 | 0.642 |
| pH | 7.425±0.022 | 7.420±0.021 | 0.1267 |
| PaO2 (mmHg) | 76.7±11.0 | 75.6±11.2 | 0.3101 |
| PaCO2 (mmHg) | 38.1±4.4 | 39.8±5.0 | 0.9654 |
| Peak CPET variables | |||
| Heart rate (beats/min) | 121±18 | 123±22 | 0.683 |
| Respiratory frequency (/min) | 33.5±7.4 | 33.2±10.4 | 0.4155 |
| Tidal volume (mL) | 942±224 | 940±312 | 0.4865 |
| Minute ventilation (L/min) | 30.7±9.1 | 29.5±9.3 | 0.2509 |
| Oxygen uptake (mL/min) | 693±192 | 705±273 | 0.605 |
| Oxygen uptake/kg | 13.6±3.8 | 13.6±4.3 | 0.5086 |
| Carbon dioxide output (mL/min) | 619±197 | 630±291 | 0.6019 |
| Oxygen pulse (mL/beat) | 5.8±1.7 | 5.6±1.9 | 0.2718 |
| Respiratory ratio | 0.89±0.11 | 0.87±0.19 | 0.2911 |
| Ventilatory equivalent for O2 | 48.0±11.2 | 45.4±12.1 | 0.126 |
| Ventilatory equivalent for CO2 | 51.0±13.4 | 49.5±16.7 | 0.2982 |
| pH | 7.362±0.031 | 7.351±0.042 | 0.0545 |
| PaO2 (mmHg) | 57.8±11.3 | 59.4±12.7 | 0.7543 |
| PaCO2 (mmHg) | 44.2±5.9 | 45.6±6.9 | 0.8594 |
| PaO2 slope (mmHg·L−1·min−1) | −52.3±36.6 | −48.8±43.6 | 0.6763 |
Notes: The PaO2 slope (mmHg·L−1·min−1) is the decrease in is the difference in between the values at rest and peak exercise.
Abbreviations: BMI, body mass index; COPD, chronic obstructive pulmonary disease; CPET, cardiopulmonary exercise testing; F, female; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; M, male; PaCO2, partial arterial pressure of carbon dioxide; PaO2, partial arterial pressure of oxygen; PPR-OT, personalized patient-specific pulmonary rehabilitation-occupational therapy; SD, standard deviation.