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. 2015 Sep 1;10:5561–5569. doi: 10.2147/IJN.S88059

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© 2015 Bai et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Effects of inhibitors, 5-aza or α-LA, on TNP-induced ROS generation in A549 cells.

Notes: The methyltransferase inhibitor, 5-aza decreased TNPs-induced ROS generation (A); the antioxidant agent, α-LA suppressed ROS generation triggered by TNPs (B). Data are expressed as mean ± SD; n=5, *P<0.05, compared with control; ^#P<0.05, compared with TNPs.

Abbreviations: 5-aza, 5-aza-2′-deoxycytidine; α-LA, α-lipoic acid; TNPs, titanium dioxide nanoparticles; ROS, reactive oxygen species; SD, standard deviation.