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. Author manuscript; available in PMC: 2015 Oct 5.

Published in final edited form as: Brain Res. 2015 Jun 20;1622:7–21. doi: 10.1016/j.brainres.2015.06.014

Fig. 2 — (A) Immunoblots and corresponding densitometric analysis (A.U., mean ± S.E.M.) of MBP showed significantly (*p < 0.001) reduced MBP isoforms (21.5, 18.5 and 14 kDa) in hippocampus, cerebellum and spinal cord in CIE 24 h (withdrawal) compared with the respective MBP isoforms in naïve mice (n = 4-6). Likewise significant reduction was seen in (B) PLP (30 kDa) and (C) CNPase-1 and-2 (46 and 48 kDa) in hippocampus in CIE 24 h (withdrawal) compared with naïve group of mice (*p < 0.0001; n = 4-6). Each immunoblot was re-probed for β-actin (42 kDa), which showed tendency towards marginal loss in CIE 24 h group compared to rest of the groups.

Fig. 2 — (A) Immunoblots and corresponding densitometric analysis (A.U., mean ± S.E.M.) of MBP showed significantly (*p < 0.001) reduced MBP isoforms (21.5, 18.5 and 14 kDa) in hippocampus, cerebellum and spinal cord in CIE 24 h (withdrawal) compared with the respective MBP isoforms in naïve mice (n = 4-6). Likewise significant reduction was seen in (B) PLP (30 kDa) and (C) CNPase-1 and-2 (46 and 48 kDa) in hippocampus in CIE 24 h (withdrawal) compared with naïve group of mice (*p < 0.0001; n = 4-6). Each immunoblot was re-probed for β-actin (42 kDa), which showed tendency towards marginal loss in CIE 24 h group compared to rest of the groups.