Fig. 3. Spontaneous seizures.

Average daily count of spontaneous seizures was derived from 6 weeks-long seizure monitoring. IL-6/KA mice developed significantly fewer, and IL-6+IL-1β/KA mice- significantly more spontaneous seizures than Saline/KA animals. Occasional rare spontaneous seizures were observed after intrahippocampal saline injection in animals of all groups. Data are shown as Mean±SEM. *-p<0.05 vs Saline+KA. Kruskal-Wallis followed by Mann-Whitney test.