Table 4.
Brain regions with a significant negative association (p<0.05, FDR-corrected) between their normalized volume and the presence of hippocampal sclerosis, according to multiple linear regression adjusting for all neuropathologies and covariates.
| Brain region | Model estimate (10−3 mm2) | p-value (FDR-corrected) |
|---|---|---|
|
| ||
| Temporal lobe | ||
| Entorhinal cortex | −0.017 | 0.0019 |
| Hippocampus | −0.037 | 0.0026 |
| Inferior temporal gyrus | −0.046 | 0.05 |
| Middle temporal gyrus | −0.07 | 0.049 |
|
| ||
| Frontal lobe | ||
| Orbitofrontal cortex (medial division) | −0.038 | 0.03 |
| Inferior frontal gyrus (pars triangularis) | −0.024 | 0.048 |
| Middle frontal gyrus (rostral division) | −0.098 | 0.04 |