Table 3.
Results of inhibition tests on CYP isozymes in the metabolism of imperatorin and isoimperatorin
The compound |
Imperatorin | Isoimperatorin |
---|---|---|
Inhibitor | ||
Blank control | / | / |
α-naphthoflavone | + | + |
quinidine | - | - |
ketoconazole | - | + |
Note : “+” represents that the inhibitor has an inhibitory effect on the metabolism, while “-” indicates no effects.