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. 2015 Aug 24;8(4):279–287. doi: 10.1016/j.tranon.2015.05.003

Figure 1.

Figure 1

Pathology of rhabdoid glioblastoma. (A) A representative H&E picture shows non-cohesive rhabdoid cells with eccentrically located pleomorphic nuclei and eosinophilic globular cytoplasm (H&E, original magnification × 200). (B) GFAP is robustly positive in some, but not all, tumor cells (GFAP immunostaining, original magnification × 200). (C) EMA is strongly positive in a cytoplasmic membrane pattern in almost all tumor cells (EMA immunohistochemistry, original magnification × 200). (D) Cyclin D1 (CCND1) staining is strongly positive in the nuclei of the tumor cells (cyclin D1 immunohistochemistry, original magnification × 200).