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. 2015 Aug 26;2015:503762. doi: 10.1155/2015/503762

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Copyright © 2015 Alejandra Sandoval-Bórquez et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(a) RPRM methylation in tumor and nontumor adjacent mucosa (NTAM) tissues: higher methylation levels in tumor tissues are observed in comparison to NTAM in all six paired GC cases (taken from [63]). (b) Histogram representing the percentage of positive cases for Reprimo and other genes (APC, SHP1, CDH-1, ER, SEMA3B, and 3OST2) in 43 prospectively collected gastric cancer cases and 31 asymptomatic age- and gender-matched controls. Only Reprimo shows significant differences in plasma between gastric cancer and asymptomatic controls (taken with permission from [68]).