Table 4.
Comparison of anti-tubercular regimens prescribed for new patients by paediatricians in private sector with standard guidelines.
| Regimens prescribed for new pulmonary TB by paediatricians in private sector | Number (%) (n = 62) |
Is prescription recommended by ISTC 2009? | Is prescription recommended by IAP? |
|---|---|---|---|
| 2 ∗ HRZE + 4 ∗ HR# | 38 (61.4) | Recommended | Recommended |
| 2 ∗ HRZ + 4 ∗ HR | 15 (24.2) | Not recommended | Recommended |
| 2 ∗ HRZ + 7 ∗ HR | 2 (3.2) | Not recommended | Recommended |
| 2 ∗ HRZE + 4 ∗ HRE | 2 (3.2) | Not recommended | Partial |
| HRZ + E | 3 (4.8) | Not recommended | Not recommended |
| HRZES | 2 (3.2) | Not recommended | Not recommended |
|
| |||
| Dosage (mg/kg) | Number (%) | ||
|
| |||
| H = 5 (n = 49) | 22 (44.9) | Lower dose | ✓ |
| H = 10 | 26 (53.1) | ✓ | ✓ |
| H = 15 | 1 (2.0) | ✓ | Higher dose |
|
| |||
| R = 10 (n = 49) | 47 (95.9) | ✓ | ✓ |
| R = 15 | 2 (4.1) | ✓ | Higher dose |
|
| |||
| Z = 15–25 (n = 47) | 32 (68.1) | Lower dose | Lower dose |
| Z = 30–35 | 13 (27.7) | ✓ | ✓ |
| Z = 35–40 | 2 (4.3) | ✓ | Higher dose |
|
| |||
| E = 15–20 (n = 40) | 14 (35) | ✓ | ✓ |
| E = 25 | 26 (65) | ✓ | Higher dose |
|
| |||
| S = 15–20 (n = 3) | 2 (66.7) | Not recommended | ✓ |
| S = 21–40 | 1 (33.3) | Not recommended | Higher dose |
ISTC—International Standard for tuberculosis care, IAP—Indian academy of paediatricians, Suggested dosages from ISTC 2009 page 37 (Original source: WHO. Treatment of tuberculosis: guidelines—4th ed. WHO/HTM/TB/2009. 420 World Health Organisation, Geneva, 2009). Drug Code: H = Isoniazid, R = Rifampicin, Z = Pyrazinamide, E = Ethambutol, S = Streptomycin. ✓ indicates that dose prescribed is in line with recommendations of ISTC or IAP, #regimen as per ISTC standard.