Table 6.
Practices of paediatricians regarding nonresponse to anti-TB treatment and diagnosis of drug-resistance among children.
| Practices regarding nonresponse to treatment | Number | Percent |
|---|---|---|
| Time of suspecting nonresponse to treatment (n = 50) | ||
| Within three months of initiation of therapy | 45 | 90.0 |
| After four or more months of therapy | 5 | 10.0 |
|
| ||
| Action taken when nonresponse is suspected (n = 58)∗ | ||
| Advise sputum culture and drug sensitivity test$ | 35 | 60.3 |
| Advise HIV test | 26 | 44.8 |
| Prescribe another regimen | 23 | 39.7 |
| Refer the patient | 6 | 10.3 |
| Assess compliance and related reasons of nonresponse | 6 | 10.3 |
| Extension of intensive phase | 1 | 1.7 |
|
| ||
| Time of requesting sputum culture and drug sensitivity for rifampicin in cases suspected for presence of drug-resistance (n = 50) | ||
| After one month of treatment with first regimen (too early) | 3 | 6.0 |
| After two or three months of treatment with first regimen# | 24 | 48.0 |
| After nonresponse to second regimen (too late) | 23 | 46.0 |
|
| ||
| Conditions when drug-resistance is suspected at beginning of treatment (n = 31)∗ | ||
| Contact with a case of drug-resistance TB# | 21 | 67.7 |
| Coinfection with HIV | 10 | 32.3 |
| History of previous treatment for TB# | 4 | 12.9 |
|
| ||
| Basis of diagnosis of drug-resistant TB (n = 51) | ||
| Including bacteriological test | 48 | 94.1 |
| Bacteriological and clinical | 30 | 58.8 |
| Bacteriological, clinical, and radiological | 14 | 27.5 |
| Bacteriological alone | 3 | 5.9 |
| Bacteriological and radiological | 1 | 2.0 |
| Excluding bacteriological test | 3 | 5.9 |
| Clinical alone | 1 | 2.0 |
| Clinical and radiological | 2 | 3.9 |
∗Multiple responses; $these 35 include 13 who also prescribe another regimen; #as per ISTC standard.