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. 2015 Aug 26;2015:960131. doi: 10.1155/2015/960131

Table 6.

Practices of paediatricians regarding nonresponse to anti-TB treatment and diagnosis of drug-resistance among children.

Practices regarding nonresponse to treatment Number Percent
Time of suspecting nonresponse to treatment (n = 50)    
 Within three months of initiation of therapy 45 90.0
 After four or more months of therapy 5 10.0

Action taken when nonresponse is suspected (n = 58)∗    
 Advise sputum culture and drug sensitivity test$ 35 60.3
 Advise HIV test 26 44.8
 Prescribe another regimen 23 39.7
 Refer the patient 6 10.3
 Assess compliance and related reasons of nonresponse 6 10.3
 Extension of intensive phase 1 1.7

Time of requesting sputum culture and drug sensitivity for rifampicin in cases suspected for presence of drug-resistance (n = 50)    
 After one month of treatment with first regimen (too early) 3 6.0
 After two or three months of treatment with first regimen# 24 48.0
 After nonresponse to second regimen (too late) 23 46.0

Conditions when drug-resistance is suspected at beginning of treatment (n = 31)∗    
 Contact with a case of drug-resistance TB# 21 67.7
 Coinfection with HIV 10 32.3
 History of previous treatment for TB# 4 12.9

Basis of diagnosis of drug-resistant TB (n = 51)    
 Including bacteriological test 48 94.1
  Bacteriological and clinical 30 58.8
  Bacteriological, clinical, and radiological 14 27.5
  Bacteriological alone 3 5.9
  Bacteriological and radiological 1 2.0
 Excluding bacteriological test 3 5.9
  Clinical alone 1 2.0
  Clinical and radiological 2 3.9

∗Multiple responses; $these 35 include 13 who also prescribe another regimen; #as per ISTC standard.