Table 3.
Chr region | Block | Haplotype | Freq case | Freq control | P-value | |||
---|---|---|---|---|---|---|---|---|
1q41 | Block 1 | rs2247421 | rs4140967 | |||||
A | C | 0.662 | 0.644 | 0.6107 | ||||
C | G | 0.298 | 0.316 | 0.5817 | ||||
C | C | 0.040 | 0.038 | 0.8593 | ||||
4p14 | Block 1 | rs10776482 | rs7694115 | rs7660429 | ||||
A | A | C | 0.547 | 0.628 | 0.021 | |||
A | G | G | 0.285 | 0.235 | 0.1147 | |||
G | G | C | 0.146 | 0.127 | 0.4271 | |||
G | A | C | 0.019 | 0.009 | 0.2357 | |||
Block 2 | rs12233670 | rs10005625 | rs5743810 | rs6531668 | ||||
C | C | G | G | 0.431 | 0.447 | 0.6687 | ||
C | C | A | A | 0.376 | 0.382 | 0.8634 | ||
T | C | G | G | 0.144 | 0.124 | 0.4179 | ||
C | C | G | A | 0.040 | 0.040 | 0.9875 | ||
4q31.3 | Block 1 | rs1992253 | rs4585282 | rs7694512 | rs13123230 | |||
C | C | G | A | 0.604 | 0.599 | 0.8859 | ||
C | C | T | G | 0.346 | 0.322 | 0.4869 | ||
C | C | G | G | 0.022 | 0.035 | 0.3251 | ||
T | C | T | G | 0.013 | 0.034 | 0.0748 | ||
Block 2 | rs1339 | rs2289318 | ||||||
T | G | 0.494 | 0.490 | 0.9195 | ||||
C | G | 0.249 | 0.257 | 0.8088 | ||||
T | C | 0.251 | 0.249 | 0.9398 | ||||
4q35.1 | Block 1 | rs11721827 | rs6552950 | rs4608848 | rs1519309 | |||
A | A | T | T | 0.248 | 0.253 | 0.8802 | ||
A | G | T | T | 0.195 | 0.233 | 0.2055 | ||
C | A | C | T | 0.192 | 0.171 | 0.4556 | ||
A | A | C | C | 0.143 | 0.166 | 0.3951 | ||
A | A | T | C | 0.133 | 0.116 | 0.4745 | ||
A | G | C | T | 0.026 | 0.013 | 0.1655 | ||
A | A | C | T | 0.038 | 0.007 | 7.0E-4* | ||
C | A | T | T | 0.012 | 0.015 | 0.6581 | ||
9q33.1 | Block 1 | rs10759932 | rs5030728 | |||||
T | G | 0.575 | 0.517 | 0.1331 | ||||
T | A | 0.223 | 0.287 | 0.0596 | ||||
C | G | 0.203 | 0.196 | 0.8298 | ||||
Xp22.2 | Block 1 | rs5935436 | rs179020 | |||||
C | G | 0.619 | 0.699 | 0.0187 | ||||
C | A | 0.333 | 0.222 | 5.0E-4* | ||||
T | G | 0.039 | 0.076 | 0.0402 | ||||
Block 2 | rs179013 | rs179008 | ||||||
G | A | 0.672 | 0.741 | 0.034 | ||||
A | T | 0.313 | 0.242 | 0.0275 | ||||
G | T | 0.011 | 0.015 | 0.6794 | ||||
Block 3 | rs10127190 | rs850632 | rs179003 | |||||
T | A | T | 0.588 | 0.601 | 0.7061 | |||
T | G | T | 0.200 | 0.207 | 0.8161 | |||
T | A | G | 0.145 | 0.135 | 0.6818 | |||
T | G | G | 0.064 | 0.052 | 0.4991 |
P ≤ 0.05 bolded.
P ≤ 0.05 after 10 000 permutations.