Venn diagram of miRNA–mRNA pairs of BLCA dataset predicted by difference databases
Correlation was calculated for all possible pair combinations of 204 miRNAs (targeting the initial five genes) and 20,501 mRNAs of the BLCA dataset. Targeting relationship was predicted with the criteria: (1) opposite correlation between the tumor and normal samples, (2) prediction by at least one database of TargetProfiler, TargetScan, and miRanda, and (3) false discovery rate <0.1.