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IFI16 is targeted to PML nuclear bodies following HSV-1 infection. Representative immunofluorescence images of HFF cells stained for IFI16 and PML in uninfected cells (Uninf.) or after infection with either WT HSV-1 or ICP0-RF at 3 and 6 hpi (m.o.i. = 1) are shown. Co-localization is indicated with white arrows. Scale bars, 5 μm.
