Table 4.

Glioma risk by glutathione S-transferase genotypes within occupational nonfarm chlorinated solvent exposure groups

	Solvent exposure						No solvent exposure
	Cases		Controls				Cases		Controls
Genotype	No.	%	No.	%	OR†	95% CI	No.	%	No.	%	OR†	95% CI
GSTM3	157/316		241/443				159/316		202/443
GSTM3 *A*A	111	71	170	71	0.91	0.57 to 1.45	119	75	142	70	1.23	0.74 to 2.05
GSTM3 *A*B or *B*B	46	29	71	29			40	25	60	30
GSTP1	160/322		245/456				162/322		211/456
GSTP1-I105V only‡	69	43	98	40	1.21	0.79 to 1.85	68	42	74	35	1.48	0.93 to 2.34
GSTP1-other genotypes§	91	57	147	60			94	58	137	65
GSTT1	159/319		240/450				160/319		210/450
GSTT1−	29	18	33	14	1.40	0.78 to 2.50	26	16	28	13	1.10	0.59 to 2.07
GSTT1+	130	82	207	86	0.72	0.40 to 1.29	134	84	182	87	0.91	0.48 to 1.71

^†Adjusted for frequency matching variables (age group, sex) and age and education, within solvent exposure groups.

^‡One or two copies of the I105V Ile->Val SNP (rs1695) but no copy of the A114V Ala->Val SNP (rs1138272).

^§Neither I105V nor A114V variant or with only A114V Ala->Val SNP.