Table II.
Tumor | Score Sensitivity | %Tumor cells Positive | H Score (intensity x % tumor cells stained) | Tumor Response | Cav-11 Expression | SPARC1 Expression |
---|---|---|---|---|---|---|
ES-6 | 3 | 95 | 285 | MCR | ND2 | ND |
ES-4 | 1 | 70 | 70 | PD1 | ND | ND |
SK-NEP-1 | 3 | 80 | 240 | MCR | 50.6 | 0.38 |
CHLA-258 | 3 | 95 | 285 | PR | 11.9 | 2.28 |
EW-8 | 3 | 100 | 300 | MCR | 47.2 | 1.01 |
EW-5 | 3 | 100 | 300 | CR | 47.9 | 0.63 |
Rh18 | 1 | 30 | 30 | PD1 | 47.9 | 6.36 |
Rh65 | 2 | 100 | 200 | MCR | 0.84 | 2.10 |
Rh10 | 0 | 0 | 0 | MCR | 0.83 | 1.43 |
Rh36 | 1 | 100 | 100 | MCR | 0.74 | 4.62 |
Rh28 | 1 | 100 | 100 | MCR | 1.3 | 2.93 |
Rh30R | 2 | 100 | 200 | CR | 1.0 | 2.39 |
Rh41 | 1 | 100 | 100 | PR | 0.89 | 2.45 |
ES-1 | 3 | 100 | 300 | MCR | ND | ND |
OS-9 | 1 | 100 | 100 | PD1 | 1.82 | 14.31 |
NB-1691 | 1 | 100 | 100 | PD1 | 0.84 | 1.12 |
TC-71 | 3 | 90 | 270 | PD2 | 32.9 | 0.6 |
NB-1643 | 1 | 100 | 100 | PD1 | 0.84 | 0.69 |
Relative expression is the ratio of the expression value for each xenograft divided by the median expression value for the entire panel.
ND, not determined.