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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Dev Dyn. 2014 Sep 11;244(3):227–238. doi: 10.1002/dvdy.24182

Table 2.

Summary of known expression and/or function of NFIs in adult stem cell populations.

Nfia Nfib Nfic Nfix
Adult neural stem cells Expressed in stem cell niches of adult CNS. (Plachez et al., 2008; Plachez et al., 2012) Expressed in stem cell niches of adult CNS. (Plachez et al., 2008; Plachez et al., 2012) Expression not examined. Expressed in stem cell niches of adult CNS. Implicated in neural stem cell quiescence. (Campbell et al., 2008; Martynoga et al., 2013)
Adult haematopoietic stem cells Moderate-high expression in adult whole bone marrow. Loss of repopulating potential after knockdown (Holmfeldt et al., 2013). Low expression. (Holmfeldt et al., 2013). Moderate-high expression in adult whole bone marrow. (Holmfeldt et al., 2013). Highly expressed in adult bone marrow. Promotes survival of HSCs and thereby repopulating potential. (Holmfeldt et al., 2013).
Hair follicle No increase in transcript levels within HFSCs relative to progeny (Tumbar et al., 2004). Transcript levels are elevated in HFSCs relative to progeny. (Tumbar et al., 2004). (Tumbar et al). No increase in transcript levels within HFSCs relative to progeny (Tumbar et al., 2004). No increase in transcript levels within HFSCs relative to progeny (Tumbar et al., 2004).
Coordinates quiescence in melanocyte stem cells (Chang et al., 2013).
Adult muscle progenitors (satellite cells) Expression unknown. Expression unknown. Expression unknown. Expression unknown.