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. 2015 Sep 8;2015(9):CD004265. doi: 10.1002/14651858.CD004265.pub3

Ladegaard 1999 DEN.

Methods Cluster‐RCT
Allocation sequence: unclear
Allocation concealment: unclear
Blinding: none
Inclusion of participants in the analysis: unclear
Length of follow‐up: 4 months
Cluster‐adjustment method: not adjusted
Participants Number: 8 day‐care centres, with 475 children (212 intervention, 263 control)
Inclusion criteria: not stated
Exclusion criteria: not stated
Age: < 6 years
Interventions Intervention (see Table 5 for detailed description):
  1. Small group practical demonstration


Control:
  1. No intervention

Outcomes Diarrhoeal rates
Notes Location: Odense, Denmark
Duration: 6 months
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Kind of unclear whether they were divided in two groups manually and then randomized or randomized stratified.
" The 8 institutions were allocated based on likeliness and randomised to intervention or control with 4 institutions in each".
Allocation concealment (selection bias) Unclear risk Randomization not described in detail.
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Not described.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Not described.
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk One institution had not written down attendance for the children 0‐2years. There were 212 children in the intervention group and 263 in the control group but no account over what happened to the children over time.
Selective reporting (reporting bias) Low risk No evidence of outcomes not presented.
Other bias Low risk None observed.