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. 2015 Sep 9;26(5):420–425. doi: 10.1097/MOL.0000000000000211

FIGURE 1.

FIGURE 1

The role of procollagen C-endopeptidase protein 2 (PCPE2) in reverse cholesterol transport. PCPE2 binds to the extracellular matrix through heparin sulphate proteoglycans. One hypothesis of how PCPE2 stimulates scavenger receptor class B1 (SR-BI) cholesteryl ester uptake suggests that PCPE2 binds to plasma HDL thereby inducing conformational changes to the lipoprotein particle promoting the removal of HDL cholesteryl ester.