Table 1. Threats to Detecting True Gene-Phenotype Associations and Solutions Offered by Ambulatory Monitoring.

Threats	Ambulatory Monitoring Solutions
1. Low phenotype reliability	1. Improved reliability through real-time assessment in a natural environment; reduced bias from recall errors
2. Low power due to small effects and small samples	2. Improved power through repeated measurements
3. Poor phenotypic specification	3. Flexible, ecologically valid phenotyping