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Candidate parameters for risk evaluation at baseline and during follow-up periods for RA-ILD patients who are scheduled for biological DMARD therapy.
| PARAMETERS | HIGH RISK FOR POOR OUTCOMES |
|---|---|
| Baseline | |
| HRCT pattern | UIP pattern |
| Severity stage | III and IV |
| DLco,% predicted | <40% predicted |
| Extent on HRCT | >20% |
| Follow-up period | |
| SpO2 after six-minute walk or equivalent | <90%, |
| Decrease in FVC | ≥10% in absolute value |
| Decrease in DLco | ≥15% in absolute value |
