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. 2015 Aug 10;34(4):1681–1691. doi: 10.3892/or.2015.4194

Figure 4.

Figure 4

Expression of MMP2, MMP9 and MMP14 and RHOC/AKT/ERK activities in RBE and HCCC-9810 cells. (A and B) Decreased relative mRNA and protein expressions of MMP2, MMP9 and the unchanged expression of MMP14 in RBE and HCCC-9810 cells. (C) Suppressed protein expression levels of RHOC, phosphorylated AKT, and phosphorylated ERK (1/2), and unchanged expression of AKT and ERK (1/2) in RBE and HCCC-9810 cells compared with the control groups. CTRL, blank control; Ne-CTRL, cells transfected with negative HOXD10 lentivirus; Lv-HOXD10, cells transfected with positive HOXD10 lentivirus; CCC, cholangiocellular carcinoma.