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. 2015 Sep 9;10(9):e0137049. doi: 10.1371/journal.pone.0137049

Fig 5. Increase in Angptl4 expression in human MCD patients and associations with desmin, synaptopodin and proteinuria.

Fig 5

(A and B) Immunofluorescence of glomerular Angptl4 and desmin in MCD and MsPGN patients with similar nephrotic-range proteinuria (magnification, 200X). (C) Immunofluorescence of glomerular Angptl4 and synaptopodin in MCD patients (magnification, 200X). (D) Immunofluorescence of glomerular Angptl4 and desmin in MCD patients (magnification, 200X). (E and F) Quantifications of the fluorescence staining intensities of glomerular Angptl4 and desmin in MCD and MsPGN patients. (G) Scatter diagram of glomerular Angptl4 and desmin in MCD patients. (H) Scatter diagram of Angptl4 and 24-hour urinary protein in MCD patients. (I) Urine Angptl4 ELISA for MCD and MsPGN patients with similar nephrotic-range proteinuria. (J) Western blot of urinary Angptl4 excretion in MCD, MN, FSGS and MsPGN patients (MCD 1,2,3, MN 1,2,3, FSGS 1 and MsPGN 4 in Table 1 are shown in the image) with similar nephrotic-range proteinuria. (K) Quantification of the western blot of urinary Angptl4 excretion in MCD, MN, FSGS and MsPGN patients. *P<0.01 compared with MsPGN patients.