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. 2015 Sep 9;10(9):e0137170. doi: 10.1371/journal.pone.0137170

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© 2015 Tornero-Esteban et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — Volcano plots representing the differential fold regulation in OA-MSCs compared to Healthy-MSCs at t = 1, 10 and 21 days of osteogenic differentiation. 84 WNT signaling pathway related genes analyzed in our study are represented. Vertical dashed lines indicate the 2.5-fold regulation cutoff. Significative genes with fold change <-2.5 and p-values <0.05 were seen only at days 10 and 21 and are indicated in S2 Table.