Table 2. Association between incomplete response and time from enrollment and culture positivity (Model A), PCR positivity (Model B), or Borrelia skin burden (log2 transformed, Model C).

	Model A: including culture positivity		Model B: including PCR positivity		Model C: including Borrelia burden
	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
Intercept	0.23 (0.12–0.43)	<0.01	0.15 (0.07–0.35)	<0.01	0.18 (0.09–0.33)	<0.01
Culture (positive vs. negative)	1.08 (0.58 to 2.03)	0.81	-	-	-	-
PCR (positive vs. negative)	-	-	1.83 (0.84 to 3.95)	0.13	-	-
Borrelial burden (log 2)	-	-	-	-	1.12 (1.00 to 1.26)	0.05
Time from diagnosis		0.05	-	0.05	-	0.04
Time 14d vs baseline	0.72 (0.36 to 1.42)	0.34	0.69 (0.35 to 1.35)	0.27	0.68 (0.35 to 1.34)	0.27
Time 2m vs 14d	0.90 (0.44 to 1.84)	0.77	0.90 (0.44 to 1.84)	0.77	0.89 (0.44 to 1.83)	0.76
Time 6m vs 2m	0.59 (0.26 to 1.32)	0.20	0.59 (0.27 to 1.32)	0.20	0.59 (0.26 to 1.31)	0.20
Time 12m vs 6m	0.96 (0.40 to 2.33)	0.93	1.06 (0.45 to 2.52)	0.89	1.07 (0.45 to 2.54)	0.88

Abbrevations: OR, odds ratio for incomplete response.