Fig 2. Effect of administration of a D4 agonist on the rGT.
A: Mean ± SEM percent choice on the advantageous choice (dark bars), omissions (grey bars) and premature responses (open bars). Administration of PD168077 produced a dose-dependent decrease in advantageous responses (n = 33; F(4, 128) = 2.992, p = 0.021, one-way ANOVA). B: Mean ± SEM number of trials initiated. No significant effects were found. C: Mean ± SEM latency to make a choice (grey bars) and latency to collect the food pellets (open bars). *Differences were found between the 5mg/kg and 10 mg/kg doses when compared to vehicle (n = 33; p<0.05). D: Ratio ± SEM perseverative responses for punished trials (grey bars) and rewarded trials (open bars). No significant effects were found.