Fig 3. Effect of administration of a D4 antagonist on the rGT.
A: Mean ± SEM percent choice on the advantageous choice (dark bars), omissions (grey bars) and premature responses (open bars). No significant effects were found. B: Mean ± SEM number of trials initiated. *Differences were found between the 1mg/kg dose and vehicle (n = 17). C: Mean ± SEM latency to make a choice (grey bars) and latency to collect the food pellets (open bars). Administration of L745870 produced a dose-dependent decrease in collect latency (n = 17; F(1, 15) = 3.419, p<0.05; one-way ANOVA). D: Ratio ± SEM perseverative responses for punished trials (grey bars) and rewarded trials (open bars). *+ A Dose X Measure interaction was revealed (F(4, 60) = 3.002, p = 0.025; n-17).