Figure 2.
Production of non-chlorinated cladoniamides C (5), H (13) and I (14) from engineered strain S. coelicolor YD17. S. coelicolor YD17 produces 5 as a major clone-specific metabolite along with cladoniamide H (13) and I (14) (detection wavelength = 211 nm). Selective ion monitoring at m/z = 404 reveals 5 as clone-specific metabolite. Selective ion monitoring at m/z = 398 reveals 13 and 14 as clone-specific metabolites.