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. Author manuscript; available in PMC: 2016 Jun 4.
Published in final edited form as: Cell. 2015 Jun 4;161(6):1252–1265. doi: 10.1016/j.cell.2015.05.023

Fig. 2. Spectrum of targets modulated by MLP probes.

Fig. 2

Target classes modulated by MLP probes are visualized based on HTS data and user-defined thresholds. Arc lengths represent the number of distinct targets within a target class that are modulated by this collection of probes. This graph was generated using the BioAssay Research Database (BARD; bard.nih.gov), which was generated by the MLP to enable users to mine and visualize small-molecule activity data. The graph depicts the bioactivity of about 65% of the total number of MLP probes across 415 unique assays associated with 460 targets, which were categorized using the Panther database into 110 protein categories. The breadth of target classes highlights the diverse biology and target space explored by the MLP.

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