Table 3.

Regression model for year 1 phenotypes in relation to GRS, exercise, and the GRS*exercise interaction

		GRS			Exercise			GRS*Exercise
		Coeff	SE	p	Coeff	SE	p	Coeff	SE	p
year 1 weight	Model 0	−0.06	0.41	0.88	–	–	–	–	–	–
	Model 1	−0.05	0.41	0.91	−0.17	0.44	0.70	–	–	–
	Model 2	−1.25	0.61	0.04	−4.82	1.85	0.01	2.10	0.81	0.01
year 1 total body fat	Model 0	126.25	378.27	0.74	–	–	–	–	–	–
	Model 1	175.75	375.25	0.64	−816.52	408.92	0.048	–	–	–
	Model 2	−940.14	564.17	0.10	−5127.43	1700.23	0.003	1945.80	745.78	0.01
year 1 total body % fat	Model 0	0.22	0.39	0.58	–	–	–	–	–	–
	Model 1	0.30	0.38	0.43	−1.30	0.41	0.002	–	–	–
	Model 2	−0.73	0.57	0.20	−5.27	1.73	0.003	1.79	0.76	0.02
year 1 lean soft tissue	Model 0	−0.17	0.18	0.33	–	–	–	–	–	–
	Model 1	−0.23	0.16	0.17	0.89	0.18	<0.001	–	–	–
	Model 2	−0.42	0.25	0.10	0.15	0.75	0.84	0.33	0.33	0.31
year 1 % lean soft tissue	Model 0	−0.19	0.39	0.63	–	–	–	–	–	–
	Model 1	−0.28	0.38	0.46	1.49	0.41	<0.001	–	–	–
	Model 2	0.58	0.57	0.31	4.81	1.73	0.01	−1.50	0.76	0.05
year 1 abdominal fat	Model 0	0.05	0.09	0.60	–	–	–	–	–	–
	Model 1	0.06	0.09	0.52	−0.17	0.10	0.09	–	–	–
	Model 2	−0.19	0.14	0.17	−1.13	0.41	0.01	0.43	0.18	0.02

Model 0: Year 1 body composition = β0 + β1*Baseline body composition + β2*GRS + error

Model 1: Year 1 body composition = β0 + β1*Baseline body composition + β2*GRS + β3*exercise + error

Model 2: Year 1 body composition = β0 + β1*Baseline body composition + β2*GRS + β3*exercise + β4*exercise*GRS +error