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. Author manuscript; available in PMC: 2016 Sep 8.
Published in final edited form as: Mol Pharm. 2015 Aug 24;12(9):3250–3260. doi: 10.1021/acs.molpharmaceut.5b00216

Figure 1.

Figure 1

Characterization of synthesized AuNPs. (a) Design of a dual-targeted AuNP loaded with Pc 4. (b) TEM of hydrophobic AuNPs. Scale bar = 100 nm. (c) Size histogram based on TEM micrographs. (d) DLS of AuNPs conjugates (left graph). UV–vis of AuNPs conjugates (right graph). (e) A 1% agarose gel at 120 V for 4 h in TAE (tris acetate EDTA) buffer. From left to right: (1) AuNPs-Pc 4, (2) EGFpep-AuNPs-Pc 4, (3) Tfpep-AuNPs-Pc 4, (4) (EGFpep+Tfpep)-AuNPs-Pc 4. (f) Stability of targeted versus untargeted AuNPs in PBS over time. Loss of Pc 4 per AuNP was measured as relative intensity of Pc 4 at 630 nm and compared to AuNP at 505 nm.