Skip to main content
. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Int J Biochem Cell Biol. 2015 May 12;67:101–109. doi: 10.1016/j.biocel.2015.04.019

Figure 2.

Figure 2

Histone modification and gene expression. While the histone is modified by repressive codes, such as H3K9 and H4K20 methylation, chromatins are condensed as heterochromatin, which close transcription effector molecules binding sites and turn off the gene transcription. Upon deposition of transcriptionally active histone codes, such as H3K4 methylation, histone acetylation and phosphorylation, the structure of chromatin will be changed into euchromatin, which opens the DNA binding sites for transcription effector molecules to initiate gene transcription.