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Effects of MBX2254 and MBX2270 on Ebola virus (EBOV) infection. The inhibitory effect of compounds MBX2254 and MBX2270 on Ebola pseudotype virus (HIV/EBOV-GP) (A, B) and infectious EBOV-Zaire (C, D). Dose-response curves for the MBX2254 and MBX2270 are shown. Infectivity was investigated as described in “Methods” section. A multiplicity of infection of 1.0 was used for infectious EBOV-Zaire. Three independent experiments were performed to determine the effects of compounds.
