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. 2015 Aug 11;5(8):e617. doi: 10.1038/tp.2015.107

Table 3. Areas of activation associated with correct recognition effect (RC>New) in the 1-back memory load in TD and ASD children.

Within-group recognition effects
Group differences
Time windows   Brain area Pseudo z-values MNI coordinates  
TD children
 375–425 R MTG 0.75 44 −7 −18  
  R Precentral gyrus 0.66 44 8 27  
400–450 R Hippocampus 0.87 42 12 18 TD>ASD
  R Precentral gyrus 0.57 49 8 27  
  R mPFC 0.54 19 48 2  
425–475 R Hippocampus 0.74 39 12 18 TD>ASD
450–500 R Hippocampus 0.52 44 −12 −18  
  R MCC 0.52 4 −27 42 TD>ASD
  R OFG 0.62 9 28 −23  
  L ACC 0.73 −1 38 22 TD>ASD
 475–525 R ACC 0.72 4 38 7  
 525–575 R OFG 0.47 24 23 −18  
               
ASD children
200–250 L dlPFC 0.52 26 18 37 ASD>TD
225–275 L dlPFC 0.64 21 23 37 ASD>TD
 400–450 R mPFC 0.89 29 53 7  
425–475 L Insula 0.84 −31 −22 22 ASD>TD
  R Insula 0.83 34 18 7 ASD>TD
450–500 R Insula 0.73 39 −2 12 ASD>TD
  R Hippocampus 0.73 29 −17 −13  
  R mPFC 0.78 29 53 7  
 500–550 L OFG 0.61 −31 43 −3  
  L ACC 0.61 −1 43 22  
 525–575 R MCC 0.66 14 −27 47  

Abbreviations: ACC, anterior cingulate cortex; ASD, autism spectrum disorder; dlPFC, dorso-lateral prefrontal cortex; L, left; MCC, middle cingulated cortex; MNI, Montreal Neurological Institute; mPFC, medial prefrontal cortex; MTG, medial temporal gyrus; OFG, orbito-frontal gyrus; PCG, precentral gyrus; R, right; RC, repeat–correct' trial; TD, typically developing.

Note: Statistical significance was set for the significant voxels of activation at P<0.05, corrected for multiple comparisons in the whole source–space volume for within-group comparisons (recognition effect in each group; RC vs New stimuli) and at P<0.005 uncorrected for between-group comparisons (recognition contrast (RC–New stimuli) by group, highlighted in bold).