Table 2.

Levels of nicotine and cotinine in brain of control and experimental animals. Values are expressed as Mean ± S.D.

Parameter	Control	Cigarette smoke (CS)	Bacoside A (BA)	Cigarette smoke + bacoside A (CS + BA)	F value
Nicotine (ng/g tissue)	n.d	180 ± 12	n.d	89 ± 5*	870.08
Cotinine (ng/g tissue)	n.d	210 ± 15	n.d	120 ± 8*	718.14

Significance is indicated for comparisons between control and CS and BA; CS versus CS + BA with Dunnett's T3 post hoc multiple comparison test; ^∗ P < 0.001.

n.d: not detected.