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Exo III activity on surfaces. (a) Exo III activity on dsDNA attached via the 3′ and 5′ ends (labeled case I and case II, respectively). (b) SPRI image and reflectivity changes during Exo III activity for case I and case II. (c) Scheme for the amplified SPRI detection of ssDNA by Exo III activity on a DNA microarray element.
