Figure 1.

(A–F) Representative experimental structures of the BH3-only protein binding interface of Bcl-xL. Bcl-xL is colored in gray except for residues 98–120, which are colored in red. The BH3-only protein binding partners (PUMA, BIM, and BAD) are shown in blue. Additional details of these PDBs are provided in Table 1. The cluster IDs are shown in parenthesis (see Table S2 for details). To see this figure in color, go online.