Table 3. Association between combined GSTP1 and GSTO1 polymorphisms and the recurrence-free survival of patients treated with epirubicin.
Epirubicin |
|||
---|---|---|---|
MST* | Log-rank P | Adjusted HR (95% CI) | |
GSTP1 and GSTO1 | |||
AG+GG and AC+AA | 31.3 | 1.00 (reference) | |
AG+GG and CC | 43.3 | 0.449 | 0.61 (0.26–1.40) |
AA and AC+AA | 57.0 | 0.051 | 0.30 (0.09–1.08) |
AA and CC | 83.4 | 0.001 | 0.21 (0.08–0.56) |
*Mean survival time was defined as the mean time before recurrence.