Table 1. Determination of the MIC of four anti-TB drugs.
Strain |
MIC (μg/ml)* |
|||
---|---|---|---|---|
INH | RIF | EMB | MMC | |
BCG/WT | 0.04 | 0.008 | 0.32 | 0.064 |
BCG/ΔinbR | 0.01 | 0.002 | 0.08 | 0.016 |
BCG/pMV261-inbR | 0.16 | 0.016 | 0.64 | 0.128 |
BCG/△inbR comp | 0.04 | 0.008 | 0.32 | 0.064 |
*M. bovis BCG was diluted to 1 × 105 cfu ml−1 and was used to inoculate 3 ml of Middlebrook 7H9 media containing various concentrations (0–1.28 μg ml−1) of four anti-TB drugs.