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. 2015 Jun 15;36(8):917–927. doi: 10.1038/aps.2015.31

Figure 5.

Figure 5

Compound 10b upregulates endogenous antioxidant systems following cerebral I/R. (A) The expression of Nrf2 in the cortex was examined by Western blot. β-Actin was used as the loading control. (B) Statistical results from the densitometric measurements after normalization to β-actin were represented as the mean±SD (n=6 for each group). (C) The representative immunoblots of HO-1 in cerebral cortex. β-Actin was used as the loading control. (D) Statistical results from the densitometric measurements after normalization to β-actin were represented as the mean±SD (n=6 for each group). (E) Representative immunoblots of Trx and Txnip. GAPDH was used as the loading control. (F) Statistical results from the densitometric measurements after normalization to GAPDH were represented as the mean±SD (n=6 for each group). Significance: bP<0.05, cP<0.01 compared with the sham group; eP<0.05, fP<0.01 compared with the I/R group by one-way ANOVA followed by Tukey's multiple comparison test.