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Trafficking patterns of A2AR Cys-to-Ala variants. HEK-293 cells transiently transfected with A2AR-CFP constructs. A–C) A2AR variants with mutations in the cysteines in ECL1. D–F) Variants with mutations in the cysteines in ECL2. G–I) Variants with mutations in the cysteines in ECL1 and ECL2 that correspond to the disulfide bonds. Scale bars, 10 µm.
