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The effect of down-regulation of miR-133a on cell migration and invasion inhibited by matrine. A. Reduced miR-133a expression by anti-miR-133a siRNA in NCI-H1299 cells detected by real-time PCR. B and C. Transwell assays were used to assess the effect of down-regulation of miR-133a on cell migration and invasion inhibited by matrine (20 µg/ml). Values are represented in a mean ± SD manner of three independent experiments (**P<0.01, ***P<0.001).
