Table 1.

Main characteristics of the studies included in the meta-analysis

Study (year)	Case	Control	CA199			CA242			CEA
			Method	Cutoff	TP/FP/FN/TN	Method	Cutoff	TP/FP/FN/TN	Method	Cutoff	TP/FP/FN/TN
Wang L (2000) [9]	130	B	ELISA	37	40/27/5/58	ELISA	21	37/34/8/51	ELISA	3.2	32/61/13/24
Liu CM (2004) [10]	74	H	ELISA	37	26/6/7/34	ELISA	20	24/5/10/35	ELISA	5	14/7/20/33
Cui LH (2008) [11]	74	B	ELISA	35	30/4/10/30	ELISA	20	28/5/12/29	ELISA	5	24/6/16/28
Dong AP (2009) [12]	165	B/H	RIA	37	45/24/9/86	RIA	20	44/26/11/84	RIA	10	36/36/19/74
Wang P (2003) [13]	64	B	CLIA	60	30/4/12/18	ELISA	20	29/6/13/16	CLIA	5	20/2/22/20
Li XM (2014) [14]	249	H	CLIA	37	90/17/39/103	ELISA	20	83/28/46/92	CLIA	5	54/41/75/79
Yang YC (2007) [15]	244	B	ELISA	37	134/20/39/51	ELISA	20	110/17/63/54	ELISA	5	53/6/120/65
Cheng J (2012) [16]	466	B/H	CLIA	35	171/6/94/195	CLIA	20	150/3/115/198	CLIA	5	102/7/163/194
Li XM (2013) [17]	229	H	CLIA	35	88/21/21/99	ELISA	20	78/19/31/101	CLIA	5	47/37/62/83
Li N (2001) [18]	123	B	CLIA	35	50/23/13/37	CLIA	20	47/10/16/50	CLIA	5	27/12/36/48
Lu C (2005) [19]	95	B/H	CLIA	37	31/16/7/41	CLIA	20	30/9/8/48	CLIA	5	23/22/15/35
Xia F (2006) [20]	138	B	CLIA	35	58/8/23/49	CLIA	20	59/6/22/51	CLIA	5	50/10/31/47
Li FM (2010) [21]	125	B	ECLIA	35	38/22/7/58	ECLIA	10	32/9/13/71	ECLIA	10	15/15/30/65
You YQ (2012) [22]	100	B	ECLIA	37	39/21/11/29	ECLIA	25	40/18/10/22	ECLIA	5	21/19/29/31
Liao Q (2007) [23]	150	B	ELISA	37	84/15/28/23	ELISA	20	66/10/46/28	ELISA	5	37/2/75/36
Zhang LZ (2008) [24]	160	B	CLIA	37	71/9/24/56	ELISA	20	71/5/24/60	CLIA	10	40/8/55/57
Yan H (2005) [25]	98	H	CLIA	35	56/6/10/26	CLIA	20	52/5/14/27	CLIA	5	45/8/21/24
Gao YC (2005) [26]	496	B	CLIA	37	236/71/79/110	RIA	20	222/52/93/129	CLIA	10	74/7/241/174
Huang BX (2011) [27]	75	B	CLIA	37	37/4/8/26	CLIA	20	28/7/17/23	CLIA	10	18/6/27/24
Zhang M (2005) [28]	146	H	MEIA	37	38/21/8/79	MEIA	20	35/11/11/89	MEIA	5	12/20/34/80
Jiang A (2011) [29]	96	H	ECLIA	35	39/12/9/36	ECLIA	20	34/11/14/37	ECLIA	5	22/13/26/35