Table 1.
Patient Characteristics for PPROM With and Without Chorioamnionitis and Control Cohorts.
| Gestational Controls (n = 12) | PPROM/No chorioamnionitis (n = 8) | PPROM/chorioamnionitis (n = 19) | P Value | |
|---|---|---|---|---|
| Maternal age, yearsa | 32 (7.3) | 29 (1.5) | 32 (5.2) | .59 |
| Nulliparity, % | 42 | 25 | 58 | .27 |
| Gestational age at birth, weeksa | 40.1 (1.4) | 32.0 (2.8) | 28.9 (3.7) | <.0001 |
| Gestational age at sampling, weeksa | 29.6 (1.2) | 32.0 (2.8) | 28.9 (3.7) | .07 |
| Birthweight, ga | 3403 (244) | 1724 (550) | 909 (487) | <.0001 |
| Latency, days | N/A | 6.4 (5-11) | 8.3 (4-28) | .32 |
| Smoking, % | 0 | 13 | 16 | .36 |
| Illicit drug use, % | 0 | 0 | 5 | .58 |
| Gestational diabetes, % | 8 | 0 | 16 | .42 |
| Antenatal corticosteroids, % | 0 | 100 | 100 | <.0001 |
| Antenatal antibiotics, % | 33 | 88 | 100 | .0001 |
| Magnesium sulfate, % | 0 | 50 | 56 | .006 |
| Placental/vaginal microbes (cases) | Group B Streptococcus (4) | Mixed flora (4) and no growth (4) | Group B Streptococcus (1), Escherichia coli (3), Acinetobacter lwoffii (1), Peptoniphilus asaccharolyticus (1), mixed anaerobic flora (3), Ureaplasma urealyticum (3), no growth (6) |
Abbreviations: SD, standard deviation; PPROM, preterm prelabor rupture of the fetal membranes; N/A, not applicable.
aMean (SD).